High molecular weight blood group A trisaccharide-polyacrylamide glycoconjugates as synthetic blood group A antigens for anti-A antibody removal devices
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چکیده
منابع مشابه
High molecular weight blood group A trisaccharide-polyacrylamide glycoconjugates as synthetic blood group A antigens for anti-A antibody removal devices.
Specific immunoadsorption of blood group antibodies by synthetic antigens immobilized on support matrices in the peri-transplantation period provides a promising solution to hyperacute rejection risk following ABO-incompatible transplantation. In this study, we investigated binding interactions between anti-A antibodies and synthetic blood group A trisaccharide conjugated with polyacrylamide of...
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Background and Aim: One of the main goals of blood transfusion medicine is to determine the compatibility of the blood products with the patients. Therefore, clinical and laboratory (serologic) evaluations should be done to determine the maximum compatibility (or minimum incompatibility). The most known blood groups is the ABO antigenic system and the most important of them is Rh system. Among ...
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Removal of blood group antibodies against the donor organ prior to ABO-incompatible transplantation can prevent episodes of hyperacute rejection. We are developing a specific antibody filter (SAF) device consisting of immobilized synthetic Atrisaccharide antigens conjugated to polyacrylamide (Atri-PAA) to selectively remove anti-A antibodies directly from whole blood. In this study, we evaluate...
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part B: Applied Biomaterials
سال: 2009
ISSN: 1552-4973,1552-4981
DOI: 10.1002/jbm.b.31466